By Julian C. Hughes
With extra humans on this planet dwelling into older age, Alzheimer's and different Dementias: The Facts takes a complete examine the unfold of dementia, and offers authoritative details and sensible recommendation for victims, their households, and the doctors who deal with them.
Written via a expert in outdated age psychiatry, the ebook offers an outline of the entire kinds of dementia (including younger-onset dementias), from the most-recognized - Alzheimer's - to the less-frequent forms, equivalent to these because of inherited metabolic problems or HIV. The booklet publications the reader step by step via how the mind works, and explains in transparent and straightforward language the impact of dementias at the mind, and the influence on an individual's cognitive function.
A committed bankruptcy explains how a analysis is reached, together with the several modes of evaluation, from blood checks conducted by way of a GP, to professional scans, highlighting how the mind really works. certain sections conceal the most recent remedies to be had, together with the arguable use of antipsychotic drugs, and the potential for disease-modifying remedies within the future.
The booklet additionally explains how the multi-disciplinary staff works jointly to appear after the sufferer's social wishes, akin to bathing and washing, in addition to their non secular and palliative wishes. Alzheimer's and different Dementias: The Facts offers the entire suitable details and tips for victims, family members and their care-givers to decide on definitely the right intervention on the correct time, to create - because the ebook advocates - a special and customized administration plan.
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Additional info for Alzheimer's and other Dementias
The protein, ApoE, is important for the metabolism of cholesterol. It is important, therefore, in heart disease. But it is also very important for neurons. After neuronal damage ApoE is released from astrocytes to help in repair. But the different alleles are more or less good at this, ε4 being poor at it. More than this, ε4 turns out to be a risk factor for Alzheimer’s disease: ◆ Having the ε4 allele increases the risk at any age; ◆ Being ε4 heterozygous (where one allele is ε4) doubles the risk; ◆ Being ε4 homozygous (where both alleles are ε4) increases the risk by six to eight times; ◆ ε4 increases the risk of Alzheimer’s disease after stroke; ◆ ε4 increases the risk after head injury.
He had long been bad at remembering names, but one day he became really confused about the names of his grandchildren and daughters-in-law. They thought this was a bit of a joke, but soon afterwards he went out to the shops and came home empty handed because he’d forgotten what he wanted to buy. He was quite upset. Then it became more obvious that he was forgetting things over a very short space of time: going into the kitchen and then not knowing what he was doing there. Gradually he also started to have problems remembering the right words.
But it is a disease of the brain that affects the ‘higher’ functions. So, for instance, a stroke might leave someone with weakness in his or her arm, but not affect the person’s ability to think. This is not dementia. As we shall see, however, a stroke in another part of the brain might have profound effects on the person’s ability to remember words or to calculate sums. It is loss of these higher functions that we call dementia. Chronic, acute, and delirium The word ‘chronic’ implies that this is a condition which lasts a long time.