Download Advances in Neuropharmacology by Giacinto Bagetta, M. Tiziana Corasaniti, T. Sakurada, S. PDF

By Giacinto Bagetta, M. Tiziana Corasaniti, T. Sakurada, S. Sakurada

This quantity offers a large evaluation of significant new advances within the box of Neuropharmacology. In 20 chapters, a range of foreign members speak about issues together with endocannabinoid functionality, ache, rigidity, astrocytes and so forth, and new probabilities for remedies of neurological illnesses with neuropharmacological techniques.

- state-of-the-art articles in neuropharmacology
- Discusses new probabilities for remedies of neurological disorders
- Very overseas authorship offering a world view of the nation of analysis

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Jane, D. , and Collingridge, G. L. (2009). Kainate receptors: Pharmacology, function and therapeutic potential. Neuropharmacology 56, 90–113. , and Ozawa, S. (2000). Kainate receptor-mediated presynaptic inhibition at the mouse hippocampal mossy fibre synapse. J. Physiol. 523, 653–665. Kehl, S. , and Collingridge, G. L. (1984). EVects of folic and kainic acids on synaptic responses of hippocampal neurones. Neuroscience 11, 111–124. , Verdoorn, T. , and Seeburg, P. H. (1990). A family of AMPA-selective glutamate receptors.

GluR7 is an essential subunit of presynaptic kainate autoreceptors at hippocampal mossy fiber synapses. Proc. Natl. Acad. Sci. USA 104, 12181–12186. Robinson, J. , and Deadwyler, S. A. (1981). Kainic acid produces depolarization of CA3 pyramidal cells in the vitro hippocampal slice. Brain Res. 221, 117–127. , and Nicoll, R. A. (2000). Synaptic activation of presynaptic kainate receptors on hippocampal mossy fiber synapses. Neuron 27, 327–338. , and Nicoll, R. A. (2001). Presynaptic kainate receptor mediation of frequency facilitation at hippocampal mossy fiber synapses.

2006). Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J. Neurosci. 26, 2852–2861. Meldrum, B. (1991). Excitotoxicity and epileptic brain damage. Epilepsy Res. 10, 55–61. Monaghan, D. , and Cotman, C. W. (1982). The distribution of [3 H]kainic acid binding sites in rat CNS as determined by autoradiography. Brain Res. 252, 91–100. GLUK1 AND HIPPOCAMPAL MOSSY FIBERS 27 More, J. , Dolman, N. , Clarke, V. , Alt, A. , Ogden, A. , Buelens, F.

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